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African Trypanosomiasis 
African trypanosomiasis, also known as sleeping sickness, is a severe disease, which is fatal if left untreated. It is closely related to a widespread infection of cattle known as N’gana, which restricts cattle rearing in many prime areas of Africa. Sleeping sickness claims comparatively few lives annually, but the risk of major epidemics means that surveillance and ongoing control measures must be maintained.
Review Articles
6 Dec 2010
Neglect of the social context
The neglected tropical diseases are attracting more research funding but the focus is still on simple biomedical interventions, ignoring the social context in which these diseases occur.
Source: Health Research Policy and Systems
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2 Jul 2010
Treating trypanosomiasis: an ironic history
A comprehensive account of the development of drugs to treat sleeping sickness.
Source: Parasites & Vectors
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News
18 Nov 2010
Reactions to the WHO report on neglected tropical diseases
What is the place for research in global efforts to control neglected tropical diseases?
Source: TropIKA.net
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16 Nov 2010
Confronting neglected protozoan diseases: understanding the challenges, developing the solutions
Scientists interested in research on neglected protozoan diseases were recently given an opportunity to hear presentations from leaders in the field, and to consider the emerging findings and progress of eight major research projects.
Source: TropIKA.net
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Editorial Opinions
14 Mar 2011
Sleeping Sickness Elimination in Sight: Time to Celebrate and Reflect, but Not Relax
Remarkable progress has been made against human African trypanosomiasis since the mid-1990s but control efforts and research should not be abandoned.
Source: PLoS Neglected Tropical Diseases
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24 Feb 2011
Funding research into the infectious diseases of poverty: what happens now?
The latest G-FINDER report says that funding for basic scientific research has increased but finances available for product development have fallen. How can funders determine where the greatest needs lie and work more closely together?
Source: TropIKA.net
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Research Articles
20 May 2010
New drugs still lacking for the infectious diseases of poverty
So far in the 21st century (and with the exception of malaria and AIDS), only four new products have become available for treating or preventing infections in poor communities.
Source: PLoS ONE
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16 Apr 2010
Sleeping sickness: could a new drug be in prospect?
Researchers have identified a molecular target for drugs to treat human African trypanosomiasis (sleeping sickness). Clinical trials of a new drug could begin as early as next year.
Source: Nature
PubMed Record |
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Reports
18 Dec 2009
Neglected disease research & development: new times, new trends
The global budget for research into the infectious diseases of poverty is little changed and AIDS continues to receive a disproportionately large share of the total. But India and Brazil are emerging as key players, particular for the more neglected diseases.
Source: George Institute
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23 Dec 2008
The World Can’t Wait: More Funding Needed for Research on Neglected Infectious Diseases
US consumer group reports on government expenditure on neglected infections and says it is not enough.
Source: Families USA
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