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African Trypanosomiasis 
African trypanosomiasis, also known as sleeping sickness, is a severe disease, which is fatal if left untreated. It is closely related to a widespread infection of cattle known as N’gana, which restricts cattle rearing in many prime areas of Africa. Sleeping sickness claims comparatively few lives annually, but the risk of major epidemics means that surveillance and ongoing control measures must be maintained.
Review Articles
2 Jul 2010
Treating trypanosomiasis: an ironic history
A comprehensive account of the development of drugs to treat sleeping sickness.
Source: Parasites & Vectors
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2 Jun 2010
Do the poor benefit from infectious disease programmes?
When interventions are planned, insufficient thought is given as to whether the poorest and most vulnerable members of society will benefit, according to the findings of a new review of the evidence. The reviewers call for more research to assess which infectious disease programmes benefit the poor and to identify the mechanisms that determine “pro-poor effectiveness”.
Source: TropIKA.net Journal
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News
13 Jul 2010
Potential TB drugs to be investigated against neglected diseases
Two not-for-profit drug developers have established a partnership that will seek to find treatments for a wide variety of neglected infections, based on a series of compounds from the nitroimidazole class.
Source: Drugs for Neglected Diseases initiative (DNDi); Global Alliance for TB Drug Development
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29 Jun 2010
Human African trypanosomiasis: number of new cases drops to lowest level in 50 years
The number of new cases of human African trypanosomiasis (also known as sleeping sickness) reported to the World Health Organization has dropped below 10,000 for the first time in 50 years.
Source: World Health Organization
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Editorial Opinions
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Research Articles
20 May 2010
New drugs still lacking for the infectious diseases of poverty
So far in the 21st century (and with the exception of malaria and AIDS), only four new products have become available for treating or preventing infections in poor communities.
Source: PLoS ONE
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16 Apr 2010
Sleeping sickness: could a new drug be in prospect?
Researchers have identified a molecular target for drugs to treat human African trypanosomiasis (sleeping sickness). Clinical trials of a new drug could begin as early as next year.
Source: Nature
PubMed Record |
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Reports
18 Dec 2009
Neglected disease research & development: new times, new trends
The global budget for research into the infectious diseases of poverty is little changed and AIDS continues to receive a disproportionately large share of the total. But India and Brazil are emerging as key players, particular for the more neglected diseases.
Source: George Institute
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23 Dec 2008
The World Can’t Wait: More Funding Needed for Research on Neglected Infectious Diseases
US consumer group reports on government expenditure on neglected infections and says it is not enough.
Source: Families USA
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