Research Articles Results  

4 Dec 2008

Extensively Drug-Resistant Tuberculosis in California, 1993–2006

Study shows that the incidence of M. tuberculosis extensively drug-resistance (XDR) strains and of those strains just one step to be become XDR TB is rapidly increasing in California
Source: Clinical Infectious Disease
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3 Dec 2008

Gender difference in knowledge of tuberculosis and associated health-care seeking behaviors: a cross-sectional study in a rural area of China

Women were found to be less likely than men to acquire knowledge about TB or to pass it on. If they have a prolonged cough, they are more likely to seek treatment but prefer local, non-hospital facilities. Most men seek care at higher-level facilities.
Source: BMC Public Health
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3 Dec 2008

Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review

More evidence will be needed before it can be concluded which drug is more effective.
Source: Malaria Journal
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28 Nov 2008

Evaluating a school-based trachoma curriculum in Tanzania

A study shows that introducing a school curriculum with the aim of changing habits or attitudes, when no teacher appropriate training is offered or no proper hygiene conditions are available, has little or no impact.
Source: Health Education Research
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25 Nov 2008

A Novel Approach to the Identification of Potential Drug Target Sites in Plasmodium falciparum

Researchers in South Africa develop a new strategy for selecting essential nucleotide sites to be used as targets for drugs against malaria.
Source: PLoS ONE
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24 Nov 2008

Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum

A study offers interesting insights on the molecular mechanism of drug resistance in P. falciparum.
Source: Molecular Microbiology
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24 Nov 2008

A DNA vaccine candidate expressing dengue-3 virus prM and E proteins elicits neutralizing antibodies and protects mice against lethal challenge

A new DNA vaccine against dengue shows promising results in DENV-3 immunized mice.
Source: Archives of Virology
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24 Nov 2008

Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria

A study done in Madagascar shows that polymorphism in P. falciparum PfHRP2 may compromise sensitivity of the rapid diagnostic test currently recommended in the country.
Source: Malaria Journal
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17 Nov 2008

Adaptive Copy Number Evolution in Malaria Parasites

Study shows that in P. falciparum, copy number variation may compensate for mutated and less efficient genes belonging to the same biochemical pathway.
Source: PLoS Genetics
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14 Nov 2008

Complexities of assessing the disease burden attributable to leishmaniasis

Assessing the burden of disease due to leishmaniasis is problematic. The authors of this review suggest how it may be more accurately estimated and how improvements can be made in monitoring the effectiveness of control programmes.
Source: PLoS Neglected Tropical Diseases
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