Research Articles Results  

10 Mar 2008

Effectiveness of single dose rifampicin in preventing leprosy in close contacts of patients with newly diagnosed leprosy: cluster randomised controlled trial

Older leprosy treatment drugs have several disadvantages for use as chemoprophylaxis. A trial of the use of a newer drug, rifampicin, found that a single dose, given to contacts of patients with newly diagnosed leprosy, is effective at preventing the development of clinical leprosy at two years.
Source: BMJ
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5 Mar 2008

Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study

Eflornithine is the only alternative to melarsoprol currently registered for the treatment of second-stage human African trypanosomiasis. A study in the Sudan shows it to have acceptable safety and effectiveness as a first-line treatment.
Source: BMJ
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1 Mar 2008

‘He will ask why the child gets sick so often’: The gendered dynamics of intra-household bargaining over healthcare for children with fever in the Volta Region of Ghana

The gendered dynamics of intra-household bargaining around treatment seeking for children with fever is investigated through qualitative research
Source: Social Science & Medicine
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18 Dec 2007

Plasmodium vivax Invasion of Human Erythrocytes Inhibited by Antibodies Directed against the Duffy Binding Protein

Christopher King and colleagues found that both rabbit and human antibodies inhibited binding of rPvDBPII to the Duffy antigen N-terminal region and to Duffy-positive human erythrocytes, suggesting that a PvDBP-based vaccine may reduce blood stage Plasmodium vivax infection.
Source: PLoS Medicine
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5 Dec 2007

Community and School-Based Health Education for Dengue Control in Rural Cambodia: A Process Evaluation

Dengue fever continues to be a major public health problem in Cambodia, with significant impact on children.
Source: PLoS Neglected Tropical Diseases
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28 Nov 2007

Enhanced Leishmania braziliensis Infection Following Pre-Exposure to Sandfly Saliva

Source: PLoS Neglected Tropical Diseases
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14 Nov 2007

Detection of Schistosoma mansoni Eggs in Feces through their Interaction with Paramagnetic Beads in a Magnetic Field

Source: PLoS Neglected Tropical Diseases
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14 Nov 2007

A Randomized Controlled Pilot Trial of Azithromycin or Artesunate Added to Sulfadoxine-Pyrimethamine as Treatment for Malaria in Pregnant Women

Source: PLoS ONE
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23 Oct 2007

Neglected Patients with a Neglected Disease? A Qualitative Study of Lymphatic Filariasis

A Sri Lankan study confirms lymphatic filariasis is associated with poor living conditions.
Source: PLoS Neglected Tropical Diseases
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28 Sep 2007

Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody

Source: PLoS Pathogens
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